Abstract
A synthetic neuraminidase substrate [2-(3′-methoxyphenyl)-N-acetyl-α-neuraminic acid] was used to detect myxo- and paramyxovirus replication in tissue culture. This method allowed estimation of viral growth even in the absence of cytopathogenic effects.
Full text
PDF


Images in this article
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Compans R. W., Dimmock N. J., Meier-Ewert H. Effect of antibody to neuraminidase on the maturation and hemagglutinating activity of an influenza A2 virus. J Virol. 1969 Oct;4(4):528–534. doi: 10.1128/jvi.4.4.528-534.1969. [DOI] [PMC free article] [PubMed] [Google Scholar]
- De Jong J. C., Winkler K. C. The multiplication of measles virus in human amnion cells in vitro. J Gen Virol. 1970 Apr;7(1):13–17. doi: 10.1099/0022-1317-7-1-13. [DOI] [PubMed] [Google Scholar]
- Howe C., Newcomb E. W., Lee L. T. The neuraminidase of measles virus. Biochem Biophys Res Commun. 1969 Feb 21;34(4):388–391. doi: 10.1016/0006-291x(69)90393-3. [DOI] [PubMed] [Google Scholar]
- Kendal A. P., Apostolov K. Production of neuraminidase in cell monolayers infected with influenza virus. Nature. 1970 Apr 11;226(5241):167–168. doi: 10.1038/226167a0. [DOI] [PubMed] [Google Scholar]
- Lipkind M. A., Tsvetkova I. V. Intracellular synthesis of myxovirus neuraminidase in chick embryo cell monolayer culture. I. Neuraminidase activity, hemagglutinin synthesis, and content of cellbound sialic acid in Newcastle disease virus-infected cells. J Virol. 1967 Apr;1(2):327–333. doi: 10.1128/jvi.1.2.327-333.1967. [DOI] [PMC free article] [PubMed] [Google Scholar]
- NOLL H., AOYAGI T., ORLANDO J. Intracellular synthesis of neuraminidase following infection of charioallantoic membranes with influenza virus. Virology. 1961 May;14:141–143. doi: 10.1016/0042-6822(61)90141-6. [DOI] [PubMed] [Google Scholar]
- SCHOLTISSEK C., ROTT R. BEHAVIOR OF VIRUS-SPECIFIC ACTIVITIES IN TISSUE CULTURES INFECTED WITH MYXOVIRUSES AFTER CHEMICAL CHANGES OF THE VIRAL RIBONUCLEIC ACID. Virology. 1964 Feb;22:169–176. doi: 10.1016/0042-6822(64)90001-7. [DOI] [PubMed] [Google Scholar]
- Seto J. T., Rott R. Functional significance of sialidose during influenza virus multiplication. Virology. 1966 Dec;30(4):731–737. doi: 10.1016/0042-6822(66)90178-4. [DOI] [PubMed] [Google Scholar]
- Tuppy H., Palese P. A chromogenic substrate for the investigation of neuraminidases. FEBS Lett. 1969 Apr;3(1):72–75. doi: 10.1016/0014-5793(69)80100-6. [DOI] [PubMed] [Google Scholar]
- Webster R. G., Laver W. G. Preparation and properties of antibody directed specifically against the neuraminidase of influenza virus. J Immunol. 1967 Jul;99(1):49–55. [PubMed] [Google Scholar]