Skip to main content
PMC home page
Journal of Virology logoLink to Journal of Virology
. 1971 Dec;8(6):856–859. doi: 10.1128/jvi.8.6.856-859.1971

Superinfection with Bacteriophage T4: Inverse Relationship Between Genetic Exclusion and Membrane Association of Deoxyribonucleic Acid of Secondary Bacteriophage 1

C J Sauri 1, C F Earhart 1
PMCID: PMC376275  PMID: 4950688

Abstract

The majority of the deoxyribonucleic acid (DNA) of superinfecting T4 bacteriophage which is injected and not hydrolyzed does not attach to host cell membrane. Low levels of association of secondary phage DNA with membrane appear to be related to temporal genetic exclusion.

Full text

PDF
856

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. BURGI E. Changes in molecular weight of DNA accompanying mutations in phage. Proc Natl Acad Sci U S A. 1963 Feb 15;49:151–155. doi: 10.1073/pnas.49.2.151. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. DULBECCO R. Mutual exclusion between related phages. J Bacteriol. 1952 Feb;63(2):209–217. doi: 10.1128/jb.63.2.209-217.1952. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Duckworth D. H. Inhibition of T4 bacteriophage multiplication by superinfecting ghosts and the development of tolerance after bacteriophage infection. J Virol. 1971 Jan;7(1):8–14. doi: 10.1128/jvi.7.1.8-14.1971. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Earhart C. F. The association of host and phage DNA with the membrane of Escherichia coli. Virology. 1970 Oct;42(2):420–436. [PubMed] [Google Scholar]
  5. Earhart C. F., Tremblay G. Y., Daniels M. J., Schaechter M. DNA replication studied by a new method for the isolation of cell membrane-DNA complexes. Cold Spring Harb Symp Quant Biol. 1968;33:707–710. doi: 10.1101/sqb.1968.033.01.079. [DOI] [PubMed] [Google Scholar]
  6. Eigner J., Block S. Host-controlled restriction of T-even bacteriophages: relation of four bacterial deoxyribonucleases to restriction. J Virol. 1968 Apr;2(4):320–326. doi: 10.1128/jvi.2.4.320-326.1968. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. FRENCH R. C., GRAHAM A. F., LESLEY S. M., VAN ROOYEN C. E. The contribution of phosphorus from T2r+ bacteriophage to progeny. J Bacteriol. 1952 Nov;64(5):597–607. doi: 10.1128/jb.64.5.597-607.1952. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Fielding P. E., Lunt M. R. The relation between breakdown of superinfecting virus deoxyribonucleic acid and temporal exclusion induced by T4 and T5 bacteriophages. J Gen Virol. 1970 Mar;6(3):333–342. doi: 10.1099/0022-1317-6-3-333. [DOI] [PubMed] [Google Scholar]
  9. Furrow M. H., Pizer L. I. Phospholipid synthesis in Escherichia coli infected with T4 bacteriophages. J Virol. 1968 Jun;2(6):594–605. doi: 10.1128/jvi.2.6.594-605.1968. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. HERSHEY A. D., CHASE M. Independent functions of viral protein and nucleic acid in growth of bacteriophage. J Gen Physiol. 1952 May;36(1):39–56. doi: 10.1085/jgp.36.1.39. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Hutchison C. A., 3rd, Sinsheimer R. L. Requirement of protein synthesis for bacteriophage phi X174 superinfection exclusion. J Virol. 1971 Jul;8(1):121–124. doi: 10.1128/jvi.8.1.121-124.1971. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. LESLEY S. M., FRENCH R. C., GRAHAM A. F., van ROOYEN C. E. Studies on the relationship between virus and host cell. II. The breakdown of T2r+ bacteriophage upon infection of its host Escherichia coli. Can J Med Sci. 1951 Jun;29(3):128–143. doi: 10.1139/cjms51-017. [DOI] [PubMed] [Google Scholar]
  13. Nossal N. G., Heppel L. A. The release of enzymes by osmotic shock from Escherichia coli in exponential phase. J Biol Chem. 1966 Jul 10;241(13):3055–3062. [PubMed] [Google Scholar]
  14. Peterson R. H., Buller C. S. Phospholipid metabolism in T4 bacteriophage infected Escherichia coli K-12 (lambda). J Virol. 1969 May;3(5):463–468. doi: 10.1128/jvi.3.5.463-468.1969. [DOI] [PMC free article] [PubMed] [Google Scholar]
  15. Silver S., Levine E., Spielman P. M. Cation fluxes and permeability changes accompanying bacteriophage infection of Escherichia coli. J Virol. 1968 Aug;2(8):763–771. doi: 10.1128/jvi.2.8.763-771.1968. [DOI] [PMC free article] [PubMed] [Google Scholar]
  16. Tessman E. S., Borrás M. T., Sun I. L. Superinfection in bacteriophage S13 and determination of the number of bacteriophage particles which can function in an infected cell. J Virol. 1971 Jul;8(1):111–120. doi: 10.1128/jvi.8.1.111-120.1971. [DOI] [PMC free article] [PubMed] [Google Scholar]
  17. VISCONTI N. Resistance to lysis from without in bacteria infected with T2 bacteriophage. J Bacteriol. 1953 Sep;66(3):247–253. doi: 10.1128/jb.66.3.247-253.1953. [DOI] [PMC free article] [PubMed] [Google Scholar]

Articles from Journal of Virology are provided here courtesy of American Society for Microbiology (ASM)

RESOURCES