Abstract
Comparable complement-fixing antigens of type 1 and type 2 herpes simplex virus were produced by extraction of infected African green monkey cells with 0.85% NaCl which was buffered at pH 9.0 with 0.05 m glycine-NaOH. The optimal antigen dilutions were higher in titrations against hyperimmune animal sera than in titrations against human sera. Complement-fixing antibody to type 2 herpes antigen was detected in 5 of 17 sera from healthy humans.
Full text
PDF![925](https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1565/376448/96520d6e3865/applmicro00121-0205.png)
![926](https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1565/376448/f6e92391419a/applmicro00121-0206.png)
![927](https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1565/376448/79869a91da47/applmicro00121-0207.png)
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Fuccillo D. A., Moder F. L., Catalano L. W., Jr, Vincent M. M., Sever J. L. Herpesvirus hominis types I and II: a specific microindirect hemagglutination test. Proc Soc Exp Biol Med. 1970 Mar;133(3):735–739. doi: 10.3181/00379727-133-34554. [DOI] [PubMed] [Google Scholar]
- GUDNADOTTIR M., HELGADOTTIR H., BJARNASON O., JONSDOTTIR K. VIRUS ISOLATED FROM THE BRAIN OF A PATIENT WITH MULTIPLE SCLEROSIS. Exp Neurol. 1964 Feb;9:85–95. doi: 10.1016/0014-4886(64)90008-1. [DOI] [PubMed] [Google Scholar]
- KISSLING R. E., REESE D. R. ANTI-RABIES VACCINE OF TISSUE CULTURE ORIGIN. J Immunol. 1963 Sep;91:362–368. [PubMed] [Google Scholar]
- Krech U., Jung M. Antigenic relationship between human cytomegalovirus, herpes simplex, and varicella-zoster virus studied by complement-fixation. Arch Gesamte Virusforsch. 1971;33(3):288–295. doi: 10.1007/BF01254685. [DOI] [PubMed] [Google Scholar]
- Nahmias A. J., Dowdle W. R. Antigenic and biologic differences in herpesvirus hominis. Prog Med Virol. 1968;10:110–159. [PubMed] [Google Scholar]
- Nahmias A. J., Dowdle W. R., Naib Z. M., Josey W. E., Luce C. F. Genital infection with Herpesvirus hominis types 1 and 2 in children. Pediatrics. 1968 Oct;42(4):659–666. [PubMed] [Google Scholar]
- Pauls F. P., Dowdle W. R. A serologic study of herpesvirus hominis strains by microneutralization tests. J Immunol. 1967 May;98(5):941–947. [PubMed] [Google Scholar]
- SCHMIDT N. J., LENNETTE E. H., SHON C. W. A complement-fixing antigen for herpes simplex derived from chick-embryo tissue cultures. Am J Hyg. 1960 Jul;72:59–72. doi: 10.1093/oxfordjournals.aje.a120134. [DOI] [PubMed] [Google Scholar]