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. Author manuscript; available in PMC: 2014 Jun 26.
Published in final edited form as: Vaccine. 2013 May 16;31(30):3079–3089. doi: 10.1016/j.vaccine.2013.04.052

Table 2.

PRCCC sensitivity of optimal vaccine allocation to epidemiological parameters of the seasonal influenza model for the five different outcome measures.

Outcome measure
Deaths Years of life loss Contingent value Infections Hospitalizations
Parameter PRCC Parameter PRCC Parameter PRCC Parameter PRCC Parameter PRCC
Recovery rate ages 0–14 0.60 Recovery rate ages 0–14 0.59 Reproductive number (R) 0.83 Reproductive number (R) 0.59 Recovery rate ages 15+ −0.56
Recovery rate ages 15+ −0.58 Recovery rate ages 15+ −0.55 Recovery rate ages 15+ −0.61 Recovery rate ages 15+ −0.58 Recovery rate ages 0–14 0.54
Reproductive number (R) 0.58 Vaccine efficacy (vs infection) ages 16–65 −0.24 Recovery rate ages 0–14 0.60 Recovery rate ages 0–14 0.55 Vaccine efficacy (vs infection) ages 16–65 −0.25

Partial rank correlation coefficients (PRCCs) were used to determine the association between the optimal proportions of individuals vaccinated in each group and input parameters of the model. The amount of vaccine was 80M doses. The PRCC of each parameter was statistically significant (P value <0.001).