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. 1972 Sep;24(3):488–494. doi: 10.1128/am.24.3.488-494.1972

Purification of Large Amounts of Murine Ribonucleic Acid Tumor Viruses Produced in Roller Bottle Cultures

James J Syrewicz 1,2,3, R B Naso 1,2,3, C S Wang 1,2,3, Ralph B Arlinghaus 1,2,3
PMCID: PMC376544  PMID: 4116893

Abstract

Murine ribonucleic acid tumor viruses and C-type virus particles are produced in relatively large quantities in roller bottle cultures. The viruses present in large volumes of culture fluids can be purified by a simple two-step procedure involving polyethylene glycol precipitation and equilibrium centrifugation in sucrose density gradients.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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