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. 1970 Jan;19(1):62–70. doi: 10.1128/am.19.1.62-70.1970

Susceptibility of Genital Mycoplasmas to Antimicrobial Agents

Peter Braun 1,2,3,1, Jerome O Klein 1,2,3,2, Edward H Kass 1,2,3
PMCID: PMC376610  PMID: 4313312

Abstract

The susceptibility of 11 T-strains, 12 strains of Mycoplasma hominis, and a single strain of M. fermentans to 15 antimicrobial agents was determined by study of inhibition of metabolic activity in a broth dilution system. All three species were inhibited by tetracycline, chloramphenicol, streptomycin, gentamicin, and kanamycin, and were relatively resistant to cephalothin, cephaloridine, polymyxin, vancomycin, and ampicillin. Three antimicrobial agents had significant differential effects on these species. Erythromycin was more active against T-strains than against M. hominis or M. fermentans. Lincomycin, clindamycin, and nitrofurantoin had greater activity against M. hominis and M. fermentans than against T-strains. The activity of the drugs tested was generally uniform over a wide range of inocula. The effect of pH and the difference between minimal inhibiting and minimal mycoplasmacidal concentrations of the drugs tested were consistent with expectations based on the effects of these drugs on bacteria.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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