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. 1970 Jan;19(1):196–198. doi: 10.1128/am.19.1.196-198.1970

Growth of Venezuelan Equine Encephalomyelitis Virus in Human Diploid Cell Strain WI-38

Morton Reitman 1, Leonard Green 1
PMCID: PMC376644  PMID: 5415216

Abstract

We demonstrated that Venezuelan equine encephalomyelitis (VEE) virus replicated in and adapted rapidly to human diploid cell strain WI-38. Peak titers of approximately 109.8 mouse intracerebral 50% lethal doses were obtained at low passage levels in Eagles basal medium supplemented with calf serum. VEE virus replicated poorly in serum-free medium. Propagation of VEE virus was accompanied by the production of hemagglutinin and cytopathogenic effects.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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