Skip to main content
Applied Microbiology logoLink to Applied Microbiology
. 1970 Feb;19(2):329–334. doi: 10.1128/am.19.2.329-334.1970

Spectra of Susceptibility of Neisseria meningitidis to Antimicrobial Agents In Vitro 1

Leonard F Devine 1, Cline R Hagerman 1
PMCID: PMC376678  PMID: 4985432

Abstract

The minimal inhibitory concentrations of 49 antimicrobial agents for 37 to 40 meningococcal strains freshly isolated from the nasopharynx of healthy carriers were determined. Coumermycin A1 and rifampin were the most effective agents tested. The geometric mean values of the minimal inhibitory concentrations for coumermycin A1 and rifampin were 0.0001 and 0.02 μg/ml, respectively.

Full text

PDF
329

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Alexander C. E., Sanborn W. R., Cherriere G., Crocker W. H., Jr, Ewald P. E., Kay C. R. Sulfadiazine-resistant group A Neisseria meningitidis. Science. 1968 Sep 6;161(3845):1019–1019. doi: 10.1126/science.161.3845.1019. [DOI] [PubMed] [Google Scholar]
  2. Devine L. F., Knowles R. C., Pierce W. E., Peckinpaugh R. O., Hagerman C. R., Lytle R. I. Proposed model for screening antimicrobial agents for potential use in eliminating meningococci from the nasopharynx of healthy carriers. Antimicrob Agents Chemother (Bethesda) 1968;8:307–314. [PubMed] [Google Scholar]
  3. Dowd J. M., Blink D., Miller C. H., Frank P. F., Pierce W. E. Antibiotic prophylaxis of carriers of sulfadiazine-resistant meningococci. J Infect Dis. 1966 Oct;116(4):473–480. doi: 10.1093/infdis/116.4.473. [DOI] [PubMed] [Google Scholar]
  4. EICKHOFF T. C., FINLAND M. CHANGING SUSCEPTIBILITY OF MENINGOCOCCI TO ANTIMICROBIAL AGENTS. N Engl J Med. 1965 Feb 25;272:395–398. doi: 10.1056/NEJM196502252720804. [DOI] [PubMed] [Google Scholar]
  5. LOVE B. D., Jr, FINLAND M. In vitro susceptibility of meningococci to eleven antibiotics and sulfadiazine. Am J Med Sci. 1954 Nov;228(5):534–539. doi: 10.1097/00000441-195411000-00006. [DOI] [PubMed] [Google Scholar]
  6. MILLAR J. W., SIESS E. E., FELDMAN H. A., SILVERMAN C., FRANK P. IN VIVO AND IN VITRO RESISTANCE TO SULFADIAZINE IN STRAINS OF NEISSERIA MENINGITIDIS. JAMA. 1963 Oct 12;186:139–141. doi: 10.1001/jama.1963.63710020008016. [DOI] [PubMed] [Google Scholar]
  7. Singer R. C. Sulfonamide-resistant meningococcal disease. Med Clin North Am. 1967 May;51(3):719–727. doi: 10.1016/s0025-7125(16)33040-1. [DOI] [PubMed] [Google Scholar]
  8. VOLLUM R. L., GRIFFITHS P. W. An experiment in the prevention of meningococcal meningitis in Nigeria. J Clin Pathol. 1962 Jan;15:50–53. doi: 10.1136/jcp.15.1.50. [DOI] [PMC free article] [PubMed] [Google Scholar]

Articles from Applied Microbiology are provided here courtesy of American Society for Microbiology (ASM)

RESOURCES