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. 1970 May;19(5):791–794. doi: 10.1128/am.19.5.791-794.1970

Viremia and Virus Measurements of Rabbit Pox in CV-1 Cells

Cheng T Cho 1,1, Thomas Locke 1, Herbert A Wenner 1,2
PMCID: PMC376790  PMID: 4316272

Abstract

Rabbit pox virus (RPV) produced cytopathic effect (CPE) in five types of cells grown in tissue cultures. The CPE on CV-1 cells was characterized by cell fusion and lysis. The CV-1 line is a useful and sensitive cell culture for measuring concentrations of RPV in blood and tissues of infected rabbits. Viremia was detected between the 2nd and 4th days after parenteral infection. By the 6th and 7th days, the concentration of RPV in various tissues ranged from 105-3 to 108-5 TCID50/g. Cross-reactivity was demonstrated by the fluorescent-antibody technique between rabbit pox, vaccinia, and monkey pox viruses.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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