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. 1970 May;19(5):830–836. doi: 10.1128/am.19.5.830-836.1970

Application of Agglutinins for the Rapid and Accurate Identification of Medically Important Candida Species 1

Charles E Sweet 1,2,2, Leo Kaufman 1,2
PMCID: PMC376797  PMID: 5463580

Abstract

Agglutinins have been prepared against the medically important Candida species. Crude antisera to the various species demonstrated intense cross-reactions with heterologous yeastlike fungi as well as with many true yeasts. However, carefully monitored adsorptions of selected antisera allowed the production of six factor sera that proved useful in a slide agglutination test. These six sera permitted the rapid and specific identification of C. guilliermondii, C. krusei, C. parapsilosis, and C. pseudotropicalis. They also allowed the delineation of two groups: (i) C. albicans (type A)-C. tropicalis and (ii) C. albicans (type B)-C. stellatoidea. C. albicans type A could be readily distinguished from C. tropicalis by its ability to form germ tubes in serum. C. stellatoidea could be distinguished from C. albicans type B by its predominantly filamentous growth on a nutritionally deficient medium. The medically important Candida species could be identified within 24 hr by the combined use of serological and morphological procedures.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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