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Applied Microbiology logoLink to Applied Microbiology
. 1970 Sep;20(3):465–468. doi: 10.1128/am.20.3.465-468.1970

Anticomplementary, Anticoagulatory, and Serum-Protein Precipitating Activity of Sodium Polyanetholsulfonate

W H Traub 1, B L Lowrance 1,1
PMCID: PMC376960  PMID: 4098638

Abstract

Sodium polyanetholsulfonate (SPS) at 7.8 μg/ml completely abolished complement-mediated hemolysis of 1:10 diluted fresh guinea pig and human serum; at least twice as much SPS was required to reduce complement activity in 1:2 diluted human serum. The coagulation of 90 and 20% human blood was inhibited by 250 and 125 μg of SPS per ml, respectively. When added to fresh human serum, SPS precipitated beta 1C-globulin (C3), C4, beta lipoproteins, immunoglobulin IgG, IgM, and IgA, though incompletely.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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