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. 1970 Oct;20(4):536–538. doi: 10.1128/am.20.4.536-538.1970

Characteristics of Growth Inhibition of Lactobacillus casei by 4-Nitroquinoline-n-Oxide

T J Bond 1, Kamie Law Young 1, Teresa Tarbell Andrus 1
PMCID: PMC376983  PMID: 5498599

Abstract

The bacteriostatic action of 4-nitroquinoline-n-oxide (4-NQO) for Lactobacillus casei is substantially reversed by d-and l-cysteine, glutathione, and 2,2-dihydroxy-1,4-dithiolbutane (dithioerythritol). The action appears to involve a chemical reaction between carbon atom 4 of 4-NQO and nucleophilic centers, such as -SH groups, located on essential cell constituents. The evidence presented indicates that the protective effect of d- and l-cysteine, glutathione, and dithioerythritol against the action involves reactions between 4-NQO and -SH compounds.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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