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. 1970 Oct;20(4):608–611. doi: 10.1128/am.20.4.608-611.1970

Bacterial Degradation of Diphenylmethane, a DDT Model Substrate

D D Focht 1,1, M Alexander 1
PMCID: PMC377000  PMID: 5498611

Abstract

A strain of Hydrogenomonas was isolated by elective culture in a solution with diphenylmethane, an analogue of DDT, as the sole carbon source. Constitutive enzymes effected the oxidation and fission of one of the benzene rings of diphenylmethane, and phenylacetic acid was found as a major degradation product. Small amounts of phenylglyoxylic and benzoic acids were also generated from diphenylmethane by the bacterium. Phenylacetic acid, which contains the second benzene ring of diphenylmethane, was metabolized by inducible enzymes.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Alexander M. Biodegradation: problems of molecular recalcitrance and microbial fallibility. Adv Appl Microbiol. 1965;7:35–80. doi: 10.1016/s0065-2164(08)70383-6. [DOI] [PubMed] [Google Scholar]
  2. DAGLEY S., EVANS W. C., RIBBONS D. W. New pathways in the oxidative metabolism of aromatic compounds by microorganisms. Nature. 1960 Nov 12;188:560–566. doi: 10.1038/188560a0. [DOI] [PubMed] [Google Scholar]
  3. Horvath R. S., Alexander M. Cometabolism of m-chlorobenzoate by an Arthrobacter. Appl Microbiol. 1970 Aug;20(2):254–258. doi: 10.1128/am.20.2.254-258.1970. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. KOJIMA Y., ITADA N., HAYAISHI O. Metapyrocatachase: a new catechol-cleaving enzyme. J Biol Chem. 1961 Aug;236:2223–2228. [PubMed] [Google Scholar]
  5. Wedemeyer G. Biodegradation of Dichlorodiphenyltrichloroethane: Intermediates in Dichlorodiphenylacetic Acid Metabolism by Aerobacter aerogenes. Appl Microbiol. 1967 Nov;15(6):1494–1495. doi: 10.1128/am.15.6.1494-1495.1967. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Wedemeyer G. Dechlorination of 1,1,1-trichloro-2,2-bis(p-chlorophenyl)ethane by Aerobacter aerogenes. I. Metabolic products. Appl Microbiol. 1967 May;15(3):569–574. doi: 10.1128/am.15.3.569-574.1967. [DOI] [PMC free article] [PubMed] [Google Scholar]

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