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. 1971 Feb;21(2):295–299. doi: 10.1128/am.21.2.295-299.1971

Antigenic Relationships Among the Proteolytic and Nonproteolytic Strains of Clostridium botulinum

H M Solomon 1, R K Lynt Jr 1, D A Kautter 1, T Lilly Jr 1
PMCID: PMC377164  PMID: 4927406

Abstract

Relationships of the somatic antigens among Clostridium botulinum strains have been investigated by tube agglutination and agglutinin absorption tests. Results revealed a relationship by which strains of C. botulinum are grouped by their proteolytic capacity rather than by the type of specific toxin produced. Thus, C. botulinum type E and its nontoxigenic variants, which are nonproteolytic, share common somatic antigens with the nonproteolytic strains of types B and F. Absorption of antiserum of a strain of any one type with antigen of any of the others removes the antibody to all three types. In the same manner, C. botulinum type A shares somatic antigens with the proteolytic strains of types B and F, and absorption of any one antiserum with an antigen of either of the other two types removes the antibody to all three types. Partial cross-agglutination of C. sporogenes, C. tetani, and C. histolyticum with the somatic antisera of the proteolytic group was also observed.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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