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. 1971 Jun;21(6):1064–1066. doi: 10.1128/am.21.6.1064-1066.1971

Effect of Toxin Concentration on the Heat Inactivation of Staphylococcal Enterotoxin A in Beef Bouillon and in Phosphate Buffer

Cleve B Denny 1, John Y Humber 1, C Wallace Bohrer 1
PMCID: PMC377344  PMID: 4998349

Abstract

The slope of the thermal inactivation curve of enterotoxin A in beef bouillon (initial pH 6.2) was found to be approximately 27.8 C (50 F) with three different concentrations of toxin. Inactivation by heat was dependent on the concentration of enterotoxin A heated. Enterotoxin A was inactivated by less heat in a pH 7.2 phosphate buffer than in beef bouillon as detected by serology. Results indicate that natural (usually low) levels of toxin rather than concentrated enterotoxin A should be used in heat inactivation studies.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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