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. 2012 Jul 11;38(11):2109–2119. doi: 10.1038/npp.2012.122

Figure 1.

Figure 1

mGluR7 levels in the nucleus accumbens (NAcc), but not in the dorsal striatum (DS), regulate ethanol-mediated place preference conditioning. (a) GR7-short hairpin RNA (shRNA) expression in the NAcc enhanced sensitivity to 0.5 g/kg of ethanol whereas expression of GR7-scr resulted in place preference at the 1 g/kg of ethanol. (b) GR7-scr and GR7-shRNA expression in the DS enhanced sensitivity only to 1 g/kg of ethanol. Data are presented as the mean±SEM. *p<0.05, **p<0.01 vs 0 g/kg of ethanol, #p<0.05 vs GR7-scr-injected group (two-way analysis of variance, Bonferroni's post hoc test).