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. 1969 Apr;17(4):611–613. doi: 10.1128/am.17.4.611-613.1969

Microneutralization Test for Determination of Rhinovirus and Coxsackievirus A Antibody in Human Diploid Cells

Robert L Kriel 1, Herta Wulff 1, Tom D Y Chin 1
PMCID: PMC377752  PMID: 4306262

Abstract

A method for determination of serum-neutralizing antibody titers to rhinovirus type 16 and coxsackievirus type A-4 in human diploid cells (WI-38) grown in Microtiter plates is described. A good correlation was observed when comparing neutralization tests in WI-38 and other cells. The WI-38 Microtiter method is relatively simple and economical. It is suitable for those laboratories which are required to conduct large-scale serological evaluation of antibodies for rhinoviruses and coxsackie A viruses. This system also can be used for cytomegalovirus and varicella-zoster virus, which grow relatively slowly.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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