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. 1969 May;17(5):695–700. doi: 10.1128/am.17.5.695-700.1969

Effect of Chloral Hydrate on Methane and Propionic Acid in the Rumen

C J Van Nevel a, H K Henderickx a, D I Demeyer a,1, J Martin a
PMCID: PMC377782  PMID: 5785952

Abstract

Methane production from pyruvate by mixed rumen bacteria in vitro was nearly totally inhibited by chloral hydrate (0.1 μmole/ml of incubation fluid). This effect was accompanied by an accumulation of gaseous hydrogen and an increase in propionic acid production. Infusion of chloral hydrate (4 g/day) into the rumen of a sheep produced the same effects. Evidence is presented for a direct toxic effect of chloral hydrate upon methane bacteria. Results are discussed in terms of fermentation balances.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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