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. Author manuscript; available in PMC: 2014 Sep 1.
Published in final edited form as: Shock. 2013 Sep;40(3):210–216. doi: 10.1097/SHK.0b013e31829efb06

Figure 1.

Figure 1

Time Line of experimental protocol. The experiment is broken into two Sections: Phase 1 – Preparation/Shock/Resuscitation: surgical preparation followed by Baseline measurements (BL) and an equilibrium period (EQ) to stabilize hemodynamics and body temperature. Following EQ, hemorrhagic shock (HS) is induced for 40min, followed by resuscitation (RES) with shed blood and Ringers Lactate. It takes approximately 70 min from the beginning of HS to the end of RES; Phase 2 – Ventilator Strategy: animals are randomized to their ventilation strategy (VC or APRV). Hemodynamics, blood gas and lung function measurements are made every 30 minutes until the end of the study at 360 minutes (T360) following RES. See Methods for detailed procedures.