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. 2013 Sep 17;62(10):3599–3609. doi: 10.2337/db13-0530

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© 2013 by the American Diabetes Association.

Readers may use this article as long as the work is properly cited, the use is educational and not for profit, and the work is not altered. See http://creativecommons.org/licenses/by-nc-nd/3.0/ for details.

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FIG. 1. — Schematic diagram of BENEDICT phase A type 2 diabetic patients screened for the Pro618Ala ADAMTS13. ACEi allocation: Ala carriers vs. Pro/Pro homozygotes, χ² = 0.715, P = 0.398. Renal event development: Ala carriers, ACEi vs. non-ACEi, χ² = 8.907, P = 0.003; Pro/Pro homozygotes, ACEi vs. non-ACEi, χ² = 5.032, P = 0.025; ACEi, Ala carriers vs. Pro/Pro homozygotes, χ² = 1.961, P = 0.161; non-ACEi, Ala carriers vs. Pro/Pro homozygotes, χ² = 1.436, P = 0.231. Cardiovascular event development: Ala carriers, ACEi vs. non-ACEi, χ² = 1.057, P = 0.304; Pro/Pro homozygotes, ACEi vs. non-ACEi, χ² = 0.218, P = 0.641; ACEi, Ala carriers vs. Pro/Pro homozygotes, χ² = 0.114, P = 0.736; non-ACEi, Ala carriers vs. Pro/Pro homozygotes, χ² = 4.673, P = 0.031. Combined event development: Ala carriers, ACEi vs. non-ACEi, χ²=8.255, P = 0.004; Pro/Pro homozygotes, ACEi vs. non-ACEi, χ² = 2.109, P = 0.146; ACEi, Ala carriers vs. Pro/Pro homozygotes, χ² = 0.747, P = 0.388; non-ACEi, Ala carriers vs. Pro/Pro homozygotes, χ² = 4.523, P = 0.033.