Skip to main content
. Author manuscript; available in PMC: 2013 Dec 13.
Published in final edited form as: Nature. 2013 May 29;498(7453):228–231. doi: 10.1038/nature12231

Figure 2.

Figure 2

Mosquito transmission of P.c. chabaudi AS transforms the elicited mammalian immune response. a-b, Number of CD8α− (open bars) and CD8α+ (closed bars) dendritic cells (a), and effector (TE) (open bars) and memory (TM) (closed bars) CD4+ T cells (b) in spleens of C57BL/6 mice injected with 105 SBP Pcc AS or infected with Pcc AS via mosquito bite. c-d, Plasma concentration of total parasite-specific IgG throughout infection (c) and parasite-specific IgG subclasses on day 80 post-infection (d) in C57BL/6 mice injected with 105 SBP Pcc AS or infected with Pcc AS via mosquito bite. Data presented as arbitrary units (AU) relative to hyper-immune plasma. e, Plasma cytokine concentration in C57BL/6 mice injected with 105 SBP Pcc AS or infected with Pcc AS via mosquito bite. (n = 3-5 mice per group per time-point; data presented as mean with SEM).