Table 2.
Effects of IFNT treatment on tissue weights of 12-week-old ZDF rats
| Tissue | Oral IFNT dose (μg/kg BW/day)
|
||
|---|---|---|---|
| 0 | 4 | 8 | |
| Abdominal fat, g | 10.8 ± 0.33a | 10.9 ± 0.72a | 6.81 ± 0.72b |
| Inguinal fat, g | 9.09 ± 0.35a | 7.43 ± 0.47b | 5.09 ± 0.49c |
| Mesenteric fat, g | 3.62 ± 0.14a | 3.53 ± 0.33a | 2.12 ± 0.14b |
| Brown adipose tissue1, g | 1.06 ± 0.12b | 1.09 ± 0.11b | 1.55 ± 0.18a |
| Liver, g | 23.6 ± 0.67a | 20.7 ± 0.30b | 18.3 ± 0.46c |
| Gastrocnemius muscle | 1.32 ± 0.05 | 1.34 ± 0.04 | 1.38 ± 0.05 |
| EDL muscle, mg | 112 ± 4 | 110 ± 4 | 110 ± 3 |
| Soleus muscle, mg | 118 ± 3 | 115 ± 4 | 115 ± 3 |
| Heart | 1.08 ± 0.03 | 1.18 ± 0.07 | 1.02 ± 0.03 |
| Lung | 1.39 ± 0.10 | 1.26 ± 0.02 | 1.34 ± 0.09 |
| Spleen | 0.54 ± 0.02 | 0.51 ± 0.02 | 0.50 ± 0.02 |
| Thymus | 0.24 ± 0.03 | 0.24 ± 0.03 | 0.25 ± 0.02 |
| Kidney | 1.54 ± 0.05 | 1.69 ± 0.05 | 1.41 ± 0.05 |
| Small Intestine | 9.81 ± 0.15 | 9.61 ± 0.37 | 9.14 ± 0.47 |
| Pancreas | 0.94 ± 0.09 | 0.97 ± 0.07 | 0.94 ± 0.10 |
| Testes | 2.84 ± 0.06 | 2.71 ± 0.04 | 2.74 ± 0.03 |
| Brain | 1.66 ± 0.05 | 1.68 ± 0.04 | 1.62 ± 0.05 |
| Large Intestine | 3.80 ± 0.23 | 3.41 ± 0.11 | 3.52 ± 0.17 |
| Stomach | 2.00 ± 0.11 | 1.93 ± 0.06 | 1.97 ± 0.13 |
Values, expressed as g, are means ± SEM, n = 6. Tissue weights were determined in 12-week-old ZDF rats. EDL = extensor digitorum.
1
Obtained from the interscapular region.