Skip to main content
. Author manuscript; available in PMC: 2014 Mar 1.
Published in final edited form as: Anesthesiology. 2013 Mar;118(3):664–678. doi: 10.1097/ALN.0b013e31828351aa

Figure 9.

Figure 9

Histology shows single Alcian Blue stained mast cells (see arrows) found in dog lumbar meninges harvested after exposure to A: vehicle, B: 10μM morphine, C/D: 100μM morphine (Bar = 20μ) E. Ex vivo histamine release from dural fragments after treatment as indicated (Mor: morphine; Nal: naloxone; Crom: cromolyn). Doses indicated are in μM indicated in legend. Each bar presents the mean ± SEM of 4–8 samples. 1-Way ANOVA analysis across treatments showed a significant main effect: p<0.0001. Post hoc using Dunnett’s multiple comparison: * p<0.05 vs. vehicle (saline).