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. Author manuscript; available in PMC: 2014 Oct 3.
Published in final edited form as: Neuron. 2013 Oct 2;80(1):64–71. doi: 10.1016/j.neuron.2013.07.014

Figure 4. Glial Glutamate Transporters Are Down-regulated in Ephrin-A2 KOs.

Figure 4

(A, B) Western blot examples and quantification reveal a down-regulation of glial glutamate transporters in the cortex of KO mice.

(C) Normalized glutamate uptake efficiencies in cortical slices of one-month-old wild-type and KO mice, with and without glial glutamate transporter inhibitors (DHK and TFB-TBOA).

(D) l-APV inhibition of eEPSCs is significantly reduced in KO cortical slices compared with wild-type slices.

(E) Percentages of spines eliminated over 4 days in wild-type mice with and without DHK treatment.

Data are presented as mean ± SEM. *P<0.05, **P<0.01. See also Figure S5.