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. Author manuscript; available in PMC: 2014 Oct 1.
Published in final edited form as: Shock. 2013 Oct;40(4):327–333. doi: 10.1097/SHK.0b013e3182a43651

Figure 1. Local G-CSF treatment reduces bacterial colonization in aged mice.

Figure 1

Young (3–4 month, gray bars) and aged (18–20 month, white bars) mice received six, 3 mm dorsal cutaneous wounds followed by ~103 CFU S. aureus/wound. 30 minutes after injury and infection, mice received either s.c. G-CSF injections (250 ng/50 μl/injection) or saline vehicle injections (50 μl/injection). At days 3 (A) and 7 (B), mice were sacrificed and bacterial colonization was determined by growth on MSA plates. Data are shown as mean ± SEM, *p<0.01 compared to young saline and **p<0.05 compared to aged saline by one-way ANOVA (A) or Mann-Whitney U test (B); N=7–14 per group.