Table 4.

Amination of 2-halopyridines.^[a]

Entry	Amine		Product (yield [%]) for the reaction with
1		(<5)	(6)	37 (60)	43 (96)
2		(<5)	no reaction	38 (65)	44 (70)
3		(<5)	no reaction	39 (48; MW 59)[b]	45 (73)
4		34 (<5)	34 (54)	40 (53)	46 (74)
5		35 (9; MW 25)[b]	35 (16)	41 (36)	47 (87)
6		36 (21)[c]	36 (46)[c]	42 (85)	48 (76)
7		no reaction	no reaction	no reaction	49 (73)

^[a]All reactions were performed with aryl halide (1 equiv.), amine (1 equiv.) and KF (2 equiv.) in water at 100 °C for 17 h.

^[b]MW refers to the yield if the reaction was performed in a microwave reactor (300 W) at 175 °C for 1 h (2 h in the case of furfurylamine) with KF (1 equiv.).

^[c]Yield reported as an NMR yield calculated from the internal standard using 1,4-dioxane.