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. 1973 Aug;26(2):146–148. doi: 10.1128/am.26.2.146-148.1973

Airborne Stability of Simian Virus 40

T G Akers 1, C M Prato 1, E J Dubovi 1
PMCID: PMC379741  PMID: 4355259

Abstract

The influence of relative humidity on the airborne survival of simian virus 40 (SV40) was studied by allowing virus aerosols to age in rotating drums at 21 or 32 C and at a relative humidity (RH) value ranging from 22 to 88%. Airborne SV40 virus was stable at every RH tested at 21 C, but aerosols maintained at 32 C were inactivated within 60 min at mid-range RH values. The unusual stability at 21 C over a broad RH range indicates that potentially biohazardous situations may occur under laboratory conditions if this virus becomes accidentally airborne.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Akers T. G., Bond S. B., Papke C., Leif W. R. Virulence and immunogenicity in mice of airborne encephalomyocarditis viruses and their infectious nucleic acids. J Immunol. 1966 Sep;97(3):379–385. [PubMed] [Google Scholar]
  2. Akers T. G., Bond S., Goldberg L. J. Effect of temperature and relative humidity on survival of airborne Columbia SK group viruses. Appl Microbiol. 1966 May;14(3):361–364. doi: 10.1128/am.14.3.361-364.1966. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Akers T. G., Hatch M. T. Survival of a picornavirus and its infectious ribonucleic acid after aerosolization. Appl Microbiol. 1968 Nov;16(11):1811–1813. doi: 10.1128/am.16.11.1811-1813.1968. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Benbough J. E. Some factors affecting the survival of airborne viruses. J Gen Virol. 1971 Mar;10(3):209–220. doi: 10.1099/0022-1317-10-3-209. [DOI] [PubMed] [Google Scholar]
  5. De Jong J. C., Harmsen M., Trouwborst T. The infectivity of the nucleic acid of aerosol-inactivated poliovirus. J Gen Virol. 1973 Jan;18(1):83–86. doi: 10.1099/0022-1317-18-1-83. [DOI] [PubMed] [Google Scholar]
  6. Dubovi E. J. Biological activity of the nucleic acids extracted from two aerosolized bacterial viruses. Appl Microbiol. 1971 Apr;21(4):761–762. doi: 10.1128/am.21.4.761-762.1971. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Ehrlich R., Miller S. Effect of relative humidity and temperature on airborne Venezuelan equine encephalitis virus. Appl Microbiol. 1971 Aug;22(2):194–199. doi: 10.1128/am.22.2.194-199.1971. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. GOLDBERG L. J., WATKINS H. M., BOERKE E. E., CHATIGNY M. A. The use of a rotating drum for the study of aerosols over extended periods of time. Am J Hyg. 1958 Jul;68(1):85–93. doi: 10.1093/oxfordjournals.aje.a119954. [DOI] [PubMed] [Google Scholar]
  9. Larson E. W., Spahn G. J., Peters R. L., Huebner R. J. Investigations of survival properties of airborne murine leukemia virus. J Natl Cancer Inst. 1970 Apr;44(4):937–941. [PubMed] [Google Scholar]
  10. TYLER M. E., SHIPE E. L. Bacterial aerosol samplers. I. Development and evaluation of the all-glass impinger. Appl Microbiol. 1959 Nov;7:337–349. doi: 10.1128/am.7.6.337-349.1959. [DOI] [PMC free article] [PubMed] [Google Scholar]

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