Abstract
In an experiment with infectious bovine rhinotracheitis (IBR) virus in two bulls, observed over a period of 122 weeks, the pattern of virus release was studied. Recurrent, unprovoked release of virus was demonstrated after one year in a nasal washing from one of the bulls and in preputial washings of both on 13 and 4 occasions, respectively, and finally in weeks 113 and 110, although clinical disease was not observed. During periods of recurrent virus release, concentrations of virus in the prepuce were generally much lower than during the period of primary infection; usually, however, they were not of negligible titer. The frequency of such periods and the virus titers observed strongly suggest that an IBR antibody carrier should always be considered as a potential source of infection to other animals. When virus was demonstrated in semen an almost equal amount was found in the preputial washing (50 ml). In week 120, virus replication in the respiratory tract and prepuce was induced in both bulls by prednisolone injections. It is concluded that antibody carriers will rarely attain a state of absolute immunity.
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Selected References
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- Bitsch V. Improved sensitivity of the IPV-IBR virus-serum neutralization test. Acta Vet Scand. 1970;11(4):606–608. doi: 10.1186/BF03547961. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Huck R. A., Millar P. G., Evans D. H., Stables J. W., Ross A. Penoposthitis associated with infectious bovine rhinotracheitis-infectious pustular vulvovaginitis (I.B.R.-I.P.V.) virus in a stud of bulls. Vet Rec. 1971 Mar 20;88(12):292–297. doi: 10.1136/vr.88.12.292. [DOI] [PubMed] [Google Scholar]
- KENDRICK J. W., GILLESPIE J. H., MCENTEE K. Infectious pustular vulvovaginitis of cattle. Cornell Vet. 1958 Oct;48(4):458–495. [PubMed] [Google Scholar]
- STUDDERT M. J., BARKER C. A., SAVAN M. INFECTIOUS PUSTULAR VULVOVAGINITIS VIRUS INFECTION OF BULLS. Am J Vet Res. 1964 Mar;25:303–314. [PubMed] [Google Scholar]
- Tomasi T. B., Jr, Bienenstock J. Secretory immunoglobulins. Adv Immunol. 1968;9:1–96. doi: 10.1016/s0065-2776(08)60441-1. [DOI] [PubMed] [Google Scholar]