Table 1.

Amino acid changes in West Nile virus (WNV) lineage 2 full genomes compared to the WNV Greece Nea Santa 2010 genome as reference.

WNV lineage 2 genomes GenBank accession number	Mature peptide amino acid position (polyprotein position)
	PrM	E				NS1				NS2A	NS2B		NS3		NS4A	NS4B			NS5
	16	88	159	166	483	69	146	187	349	1	18	119	244	249	86	14	49	113	25	227	298	446	650
	139	378	449	456	773	860	937	978	1140	1144	1392	1493	1749	1754	2210	2287	2322	2386	2554	2756	2827	2975	3179
Greece Nea Santa 2010 HQ537483	A	P	I	R	M	E	A	A	R	Y	V	I	Q	P	I	G	A	M	T	G	A	R	T
WNV-2/ GR/2012/39 KF179639	.	.	.	K	V	.	V	.	K	.	A	.	.	.	.	.	.	.	.	.	.	.	.
Austria 2008 KF179640	.	.	.	.	.	.	.	.	.	.	.	V	.	H	.	S	T	V	.	.	.	.	.
Hungary 04 DQ116961	.	S	.	.	.	G	.	.	.	H	.	V	.	H	.	S	T	V	A	.	.	.	.
Italy-AN-2 2011 JN858070	V	.	T	.	.	.	.	V	.	.	.	V	.	H	T	S	T	V	.	S	T	H	A
Serbia 2012 KC407673	.	.	.	.	.	.	.	.	.	.	.	V	H	H	.	S	T	V	.	.	.	.	.

Amino acid changes in the WNV lin2 genomes compared to the WNV Nea Santa genome as reference are reported in the table. (.): no amino acid change.