Abstract
The metabolism of the fungicide Dexon (p-dimethylaminobenzenediazo sodium sulfonate) by a soil bacterium is reported for the first time. The organism which is capable of using Dexon only by a co-metabolic process was obtained by enrichment culture and was identified as Pseudomonas fragi. The first metabolic product of Dexon was identified as N,N-dimethyl-p-phenylenediamine. The presence of an enzyme, p-dimethylaminobenzenediazo sodium sulfonate reductase, capable of reducing Dexon to N,N-dimethyl-p-phenylenediamine has been demonstrated in the cell-free extracts of the organism. The enzyme is found to be in the soluble fraction and requires dithiothreitol as a reductant.
Full text
PDF



Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- MILLER J. A., MILLER E. C. The carcinogenic aminoazo dyes. Adv Cancer Res. 1953;1:339–396. doi: 10.1016/s0065-230x(08)60007-x. [DOI] [PubMed] [Google Scholar]
- SEUBERT W. Degradation of isoprenoid compounds by micro-organisms. I. Isolation and characterization of an isoprenoid-degrading bacterium, Pseudomonas citronellolis n. sp. J Bacteriol. 1960 Mar;79:426–434. doi: 10.1128/jb.79.3.426-434.1960. [DOI] [PMC free article] [PubMed] [Google Scholar]
