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Applied Microbiology logoLink to Applied Microbiology
. 1974 Jan;27(1):43–46. doi: 10.1128/am.27.1.43-46.1974

Conversion of Dexon (p-Dimethylaminobenzenediazo Sodium Sulfonate) to N,N-Dimethyl-p-Phenylenediamine by Pseudomonas fragi Bk9

N G K Karanth 1,2, S G Bhat 1,2, C S Vaidyanathan 1,2, V N Vasantharajan 1,2
PMCID: PMC379965  PMID: 4809909

Abstract

The metabolism of the fungicide Dexon (p-dimethylaminobenzenediazo sodium sulfonate) by a soil bacterium is reported for the first time. The organism which is capable of using Dexon only by a co-metabolic process was obtained by enrichment culture and was identified as Pseudomonas fragi. The first metabolic product of Dexon was identified as N,N-dimethyl-p-phenylenediamine. The presence of an enzyme, p-dimethylaminobenzenediazo sodium sulfonate reductase, capable of reducing Dexon to N,N-dimethyl-p-phenylenediamine has been demonstrated in the cell-free extracts of the organism. The enzyme is found to be in the soluble fraction and requires dithiothreitol as a reductant.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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