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. 1974 Jan;27(1):59–65. doi: 10.1128/am.27.1.59-65.1974

Inactivation of Encephalomyocarditis Virus in Aerosols: Fate of Virus Protein and Ribonucleic Acid

J C De Jong 1, M Harmsen 1, T Trouwborst 1, K C Winkler 1
PMCID: PMC379968  PMID: 4358862

Abstract

After aerosolization at relative humidities of 50% or lower, encephalomyocarditis virus is rapidly inactivated. In this process the protein coat of the virion is damaged. This appears as a loss of hemagglutination activity and loss of affinity for hemagglutination inhibiting antibodies. The ribonucleic acid of the virus retains its infectivity but it becomes susceptible to ribonuclease. It sediments in sucrose gradients when centrifuged at high speed with the same velocity as free infectious ribonucleic acid extracted with phenol from intact encephalomyocarditis virus.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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