Skip to main content
NCBI home page
Applied Microbiology logoLink to Applied Microbiology
. 1974 Jan;27(1):130–134. doi: 10.1128/am.27.1.130-134.1974

Microbial Reduction of Ketopantoyl Lactone to Pantoyl Lactone1

Raymond P Lanzilotta a, Dorothy G Bradley a, Kerry M McDonald a
PMCID: PMC379980  PMID: 4589122

Abstract

The results of a microbial survey study have shown that the ability to reduce added ketopantoic acid (or ketopantoyl lactone) and accumulate pantoic acid (or pantoyl lactone) in the growth medium is widespread among diverse fungi. The reductions generally proceeded with less than full stereoselectivity. However, specific strains of the ascomycete Byssochlamys fulva were found to form D[-]-pantoic acid in unusually high yields and optical purity.

Full text

PDF
130

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. ADLER H. I., HARDIGREE A. A. ANALYSIS OF A GENE CONTROLLING CELL DIVISION AND SENSITIVITY TO RADIATION IN ESCHERICHIA COLI. J Bacteriol. 1964 Mar;87:720–726. doi: 10.1128/jb.87.3.720-726.1964. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. BROWN G. M., REYNOLDS J. J. BIOGENESIS OF THE WATER-SOLUBLE VITAMINS. Annu Rev Biochem. 1963;32:419–462. doi: 10.1146/annurev.bi.32.070163.002223. [DOI] [PubMed] [Google Scholar]
  3. GRULA E. A., GRULA M. M. Cell division in a species of Erwinia III. Reversal of inhibition of cell division caused by D-amino acids, penicillin, and ultraviolet light. J Bacteriol. 1962 May;83:981–988. doi: 10.1128/jb.83.5.981-988.1962. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. GRULA M. M., GRULA E. A. Cell division in a species of Erwinia IV. Metabolic blocks in panothenate biosynthesis and their relationship to inhibition of cell division. J Bacteriol. 1962 May;83:989–997. doi: 10.1128/jb.83.5.989-997.1962. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Kirby E. P., Ruff W. L., Goldthwait D. A. Cell division and prophage induction in Escherichia coli: effects of pantoyl lactone and various furan derivatives. J Bacteriol. 1972 Aug;111(2):447–453. doi: 10.1128/jb.111.2.447-453.1972. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. LANSFORD E. M., SHIVE W. The microbiological activity of alpha-keto-beta beta-dimethyl-alpha-butyrolactone. Arch Biochem Biophys. 1952 Jul;38:353–355. doi: 10.1016/0003-9861(52)90040-4. [DOI] [PubMed] [Google Scholar]
  7. MACLEOD R., PROSSER H., FIKENTSCHER L., LANYI J., MOSHER H. S. ASYMMETRIC REDUCTIONS. 12. STEREOSELECTIVE KETONE REDUCTIONS BY FERMENTING YEAST. Biochemistry. 1964 Jun;3:838–846. doi: 10.1021/bi00894a020. [DOI] [PubMed] [Google Scholar]
  8. VAN DE PUTTE P., WESTENBROEK C., ROERSCH A. THE RELATIONSHIP BETWEEN GENE-CONTROLLED RADIATION RESISTANCE AND FILAMENT FORMATION IN ESCHERICHIA COLI. Biochim Biophys Acta. 1963 Oct 15;76:247–256. doi: 10.1016/0006-3002(63)90037-4. [DOI] [PubMed] [Google Scholar]

Articles from Applied Microbiology are provided here courtesy of American Society for Microbiology (ASM)

RESOURCES