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PTP opening-dependent delayed [Ca2+]c dysregulation in suspensions of permeabilized cells.: [Ca2+]c was measured using fura2FF/FA in suspensions of permeabilized HepG2 (left) and H9c2 (right) cells exposed to pro-apoptotic stimuli. C2 (40 µM, purple), H2O2 (50/200 µM, red) or solvent (black) were added 180 s before Ca2+ pulsing. The measurements were repeated in the presence of CsA (5 uM, blue). Traces are shown from separate incubations using the same cell preparation.
