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. 1974 Apr;27(4):777–783. doi: 10.1128/am.27.4.777-783.1974

Production of a Potent Vaccine from the Attenuated M-44 Strain of Coxiella burneti

David M Robinson 1, Sherman E Hasty 1
PMCID: PMC380134  PMID: 4825980

Abstract

The attenuated M-44 strain of Coxiella burneti was heated to free it of adventitious agents that may have been present. Parallel titrations of the strain before and after heating indicated that the virulence for guinea pigs was markedly decreased. Guinea pigs immunized with the strain derived after heat treatment were protected from the effects of challenge with C. burneti in either phase I or II.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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