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The Journal of Clinical Investigation logoLink to The Journal of Clinical Investigation
. 2000 Aug 15;106(4):607. doi: 10.1172/jci8604c1

A novel signaling mechanism between gas and blood compartments of the lung

Wolfgang M Kuebler, Kaushik Parthasarathi, Ping M Wang, Jahar Bhattacharya
PMCID: PMC380260  PMID: 10953036

During the preparation of this manuscript for publication, an error was introduced in Figure 7. The correct version, accompanied by the legend, appears below.

Figure 7.

Figure 7

Effects of cPLA2 and its products. (a and b) Tracings from single experiments. Alveolar or capillary routes of TNF-α infusion are indicated. Replicated 4 times each. (c) Group data for indicated inhibitors given in 10-minute alveolar infusions before alveolar infusion of TNF-α; n = 4 for each. AP < 0.05 vs. baseline (open bar). BP < 0.05 vs. TNF-α (solid bar). COCF3, AACOCF3; indo, indomethacin; MK, MK886; WEB, WEB 2170BS. (d) Alveoli were permeabilized by 10-minute saponin infusions. Then arachidonate was infused into permeabilized (closed circles) and control (open circle) alveoli. Each point is the mean ± SEM of 4 experiments. Line was drawn by linear regression (P < 0.001).


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