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. 1972 May;23(5):951–952. doi: 10.1128/am.23.5.951-952.1972

Comparative Immunogenicities of Chikungunya Vaccines Propagated in Monkey Kidney Monolayers and Chick Embryo Suspension Cultures

Arthur White 1, Sanford Berman 1, Joseph P Lowenthal 1
PMCID: PMC380477  PMID: 4624213

Abstract

A comparative study was made of Formalin-inactivated Chikungunya vaccines prepared from the virus propagated in African green monkey kidney monolayers and concentrated chick embryo suspension cultures. The vaccine prepared in the chick embryo suspension cultures was significantly more protective to mice against a live homologous virus challenge and stimulated the production of 4 to 5 times more circulating antibodies than the vaccine prepared with virus grown in African green monkey kidney monolayer cultures.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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