Abstract
Streptomyces griseus ATCC 10137 synthesizes about 1 IU of L-asparaginase/100 ml of a 4% peptone medium. The enzyme has a pH optimum of 8.5 which is comparable to that of the L-asparaginase derived from Escherichia coli which has antitumor properties.
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Selected References
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- Campbell H. A., Mashburn L. T., Boyse E. A., Old L. J. Two L-asparaginases from Escherichia coli B. Their separation, purification, and antitumor activity. Biochemistry. 1967 Mar;6(3):721–730. doi: 10.1021/bi00855a011. [DOI] [PubMed] [Google Scholar]
- Heinemann B., Howard A. J. Production of tumor-inhibitory L-asparaginase by submerged growth of Serratia marcescens. Appl Microbiol. 1969 Oct;18(4):550–554. doi: 10.1128/am.18.4.550-554.1969. [DOI] [PMC free article] [PubMed] [Google Scholar]
- PRIDHAM T. G., ANDERSON P., FOLEY C., LINDENFELSER L. A., HESSELTINE C. W., BENEDICT R. G. A selection of media for maintenance and taxonomic study of Streptomyces. Antibiot Annu. 1956:947–953. [PubMed] [Google Scholar]
- Reddy V. V., Jayaram H. N., Sirsi M., Ramakrishnan T. Inhibitory activity of L-asparaginase from Mycobacterium tuberculosis on Yoshida ascites sarcoma in rats. Arch Biochem Biophys. 1969 Jun;132(1):262–267. doi: 10.1016/0003-9861(69)90361-0. [DOI] [PubMed] [Google Scholar]
- Roberts J., Burson G., Hill J. M. New procedures for purification of L-asparaginase with high yield from Escherichia coli. J Bacteriol. 1968 Jun;95(6):2117–2123. doi: 10.1128/jb.95.6.2117-2123.1968. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Zanin V. A., Berezov T. T., Nikolaev A. Ia, Abdumalikov A. Kh. Obrazovanie L-asparaginazy u nekotorykh mikroorganizmov. Mikrobiologiia. 1969 May-Jun;38(3):432–436. [PubMed] [Google Scholar]