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The combined use of UV/IR microdissection with NIA increases the informative potential of size-limited human biopsy specimens. The use of fresh-frozen tissues, cryosectioning and microdissection enables the acquisition of histological, genetic and proteomic data. Histopathological scoring shows H&E staining of representative normal colonic mucosa, distended and serrated hyperplastic ACF (all images shown at 200x magnification).
