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. 1972 Dec;24(6):924–928. doi: 10.1128/am.24.6.924-928.1972

Quantitation of the Bioenergetics of a Tuberculosis Infection in Chicks

R L Squibb 1,2, M Solotorovsky 1,2, W R Beisel 1,2
PMCID: PMC380697  PMID: 4650598

Abstract

Interaction of an avian tuberculosis infection with a known metabolizable energy yield of dietary corn oil in chicks was used to quantitate total host energy expenditure necessitated by the infectious process. Three trials in which two doses of inoculum were used resulted in mild and severe involvements. Trial 1 (mild) indicated that 6% and trials 2 and 3 (severe) that 96 and 93% of the energy supplied by known quantities of corn oil were utilized by the tuberculosis process. In the birds given the low level of inoculum, the degree of tuberculosis involvement, as measured by increased liver size, was correlated with increased total quantities of hepatic ribonucleic acid, monoglycerides, free fatty acids, free cholesterol, and glucose. All of these effects were observed prior to manifestations of clinical symptoms or failure of the chicks to consume all food offered.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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