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. 1973 Jun;25(6):862–868. doi: 10.1128/am.25.6.862-868.1973

Microbial Formation of Nitrosamines In Vitro

Abateni Ayanaba a,1, Martin Alexander a
PMCID: PMC380930  PMID: 4577486

Abstract

Mortierella parvispora and an unidentified bacterium converted trimethylamine to dimethylamine, and the bacterium (but not the fungus) formed dimethylnitrosamine in the presence of nitrite. Dimethylnitrosamine also appeared in cell suspensions of Escherichia coli and Streptococcus epidermidis and in hyphal mats of Aspergillus oryzae incubated with dimethylamine and nitrate. Suspensions of a number of microorganisms produced N-nitrosodiphenylamine from diphenylamine and nitrite at pH 7.5, and soluble enzymes catalyzing the N-nitrosation of diphenylamine were obtained from two of these organisms. In the presence of these enzymes, several dialkylamines were converted to the corresponding N-nitroso compounds.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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