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. 2012 Jun 14;33(1):1–10. doi: 10.3233/DMA-2012-0904

Cancer Biomarker Discovery: Lectin-Based Strategies Targeting Glycoproteins

David Clark 1, Li Mao 1,*
PMCID: PMC3810786  PMID: 22710864

Abstract

Biomarker discovery can identify molecular markers in various cancers that can be used for detection, screening, diagnosis, and monitoring of disease progression. Lectin-affinity is a technique that can be used for the enrichment of glycoproteins from a complex sample, facilitating the discovery of novel cancer biomarkers associated with a disease state.

Keywords: Lectins, lectin-affinity, biomarkers, glycosylation, glycoproteins

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