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. 2013 Sep 30;3:42. doi: 10.4103/2156-7514.119149

Imaging of Tuberculosis of the Abdominal Viscera: Beyond the Intestines

Saurabh Karmakar 1,, Alok Nath 1, Hira Lal 1
PMCID: PMC3814615  PMID: 24255797

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Dear Editor,

This is with regards to an article titled “Imaging of tuberculosis of the abdominal viscera: Beyond the intestines,” published in your journal.[1] We read the article with interest and have the following comments to offer.

The statement made by the authors, that “genitourinary tuberculosis has been reported to be the most common site for extrapulmonary tuberculosis” is incorrect.

The reference cited by the authors is from a retrospective analysis of 397 patients in Turkey. Data from the larger population based studies do not support this assertion. Surveillance studies from the US and Europe reveal the largest proportion of extrapulmonary tuberculosis cases is lymph node (37.2% and 30.5%) and pleural tuberculosis (16.9% and 36.7%).[2,3] Pleura (60%) and lymph node (14%) are the major sites of extrapulmonary disease in East Africa.[4] In India, which has a third of world's tuberculosis cases, lymph node tuberculosis is the most common form of extrapulmonary tuberculosis.[5]

Genitourinary tuberculosis comprises 6.9%, 5%, and less than 5% of all extrapulmonary tuberculosis cases in Europe, US, and Africa/India respectively.[3,4,5] Regarding the high frequency of genitourinary tuberculosis, the authors have cited studies that refer to a survey of extrapulmonary tuberculosis by Farer et al., in 1979 during the pre-acquired immunodeficiency syndrome (AIDS) era.[6] In subsequent years, AIDS related immunosuppression in patients, led to dissemination to different organ systems and a decline in the relative frequency of genitourinary tuberculosis.[7]

Footnotes

REFERENCES

  • 1.Tirumani SH, Ojili V, Gunabushanam G, Shanbhogue AK, Nagar A, Fasih N, et al. Imaging of tuberculosis of the abdominal viscera: Beyond the intestines. J Clin Imaging Sci. 2013;3:17. doi: 10.4103/2156-7514.111234. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 2.Sandgren A, Hollo V, van der Werf MJ. Extrapulmonary tuberculosis in the European Union and European Economic Area, 2002 to 2011. Euro Surveill. 2013;18:20431. [PubMed] [Google Scholar]
  • 3.Atlanta, GA: US Department of Health and Human Services, CDC; 2011. [Last accessed on 2012 Feb 21]. CDC. Reported tuberculosis in the United States, 2010. Available from: http://www.cdc.gov/tb/statistics/reports/2010/default.htm . [Google Scholar]
  • 4.Harries AD. Tuberculosis in Africa: Clinical presentation and management. Pharmacol Ther. 1997;73:1–50. doi: 10.1016/s0163-7258(96)00115-5. [DOI] [PubMed] [Google Scholar]
  • 5.Wares F, Balasubramanian R, Mohan A, Sharma SK. Extrapulmonary tuberculosis: Management and control. In: Agarwal SP, Chauhan LS, editors. Tuberculosis Control in India. New Delhi: Elsevier, Directorate General Health Services; 2005. pp. 95–114. Ministry of Health and Family Welfare. [Google Scholar]
  • 6.Farer LS, Lowell AM, Meador MP. Extrapulmonary tuberculosis in the United States. Am J Epidemiol. 1979;109:205–17. doi: 10.1093/oxfordjournals.aje.a112675. [DOI] [PubMed] [Google Scholar]
  • 7.Kwara A, Roahen-Harrison S, Prystowsky E, Kissinger MR, Adams R, Mathison J, et al. Manifestations and outcome of extra-pulmonary tuberculosis: Impact of human immunodeficiency virus co-infection. Int J Tuberc Lung Dis. 2005;9:485–93. [PubMed] [Google Scholar]
J Clin Imaging Sci. 2013 Sep 30;3:42.

Authors Reply

Vijayanadh Ojili 1

We thank Dr. Karmakar for his valuable comments on our article. While we agree with the fact that lymph node and pleura are the most common site of tuberculosis outside the lungs, we would like to emphasize the fact that the comment made in our article was in the context of extra-thoracic tuberculosis in general and solid abdominal visceral tuberculosis in particular. Though the semantics of the comment can be dwelled upon in depth, our intention was to highlight the significance of solid visceral tuberculosis in the abdomen.


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