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Journal of Antimicrobial Chemotherapy logoLink to Journal of Antimicrobial Chemotherapy
. 2013 Sep 20;68(12):2964–2965. doi: 10.1093/jac/dkt380

One hundred and twelve infected arthroplasties treated with ‘DAIR’ (debridement, antibiotics and implant retention): antibiotic duration and outcome

I Byren, P Bejon, B L Atkins, B Angus, S Masters, P McLardy-Smith, R Gundle, A Berendt
PMCID: PMC3820110

J Antimicrob Chemother 2009; 63: 1264–71

Two row labels and two data items in each of these rows in Table 1 were misplaced and this affects one of the reported results. The corrected Table is reproduced below, with the altered data shown in bold. The change to the results concerns the ninth paragraph of the Results, referring to these data in Table 1.

Table 1.

HRs from survival analysis (Cox regression) for the association of individual factors with failure

Variable/category n Number failing Hazard ratio 95% CI P
Gender
 female 50 10 1
 male 62 10 0.7 0.30–1.73 0.47
Age (years)
 <40 2 0
 40–49 2 1
 50–59 22 4 1
 60–69 34 5 0.8 0.21–3 0.75
 70–79 35 7 1.2 0.35–4.1 0.86
 80–89 17 3 1.1 0.26–5.13 0.92
Co-morbidity
 none 45 4 1
 one or more 66 15 2.7 0.91–8.3 0.07
 unknown 1 1
Time from implant to debridement (days)
 <90 77 9 1
 ≥90 35 11 3.0 1.2–7.2 0.016
Time from presentation to debridement (days)
>14 16 5 1
 3–14 25 6 0.77 0.24–2.5 0.67
<3 71 9 0.36 0.12–1.0 0.07
Arthroplasty
 primary implant 86 11 1
 revised implant 26 9 2.6 1.1–6.3 0.031
Surgical debridement
 open debridement 97 12 1
 arthroscopy 15 8 5.4 2.2–13 <0.0005
Joint
 hip 52 7 1
 knee 51 13 0.47 0.19–1.18 0.10
 ankle 3 0
 shoulder 2 0
 elbow 4 0
Surgical findings
 no pus at surgery 54 8 1
 pus at surgery 48 1 1.5 0.59–3.65 0.41
 unknown 10 11
Number of debridements
 single procedure 88 14 1
 multiple procedures 24 6 1.8 0.68–4.7 0.24
Microbiologya
 MRSA 9 3 2.0 0.59–7 0.26
 MSSA 39 10 1.8 0.71–4.4 0.21
 CoNS 26 5 1.0 0.36-2.8 0.99
S. aureus 47 13 2.6 0.97-6.9 0.052
Intravenous antibiotics
 <28 days 26 8 1
 ≥28 days 86 12 0.41 0.16–0.99 0.050

MRSA, methicillin-resistant S. aureus; MSSA, methicillin-susceptible S. aureus; CoNS, coagulase-negative staphylococci.

aMultiple organisms can be isolated from one patient, hence the sum of n is >112.

The original text read ‘There was a trend towards better outcomes in patients with a longer time between presentation and debridement (Table 1) on univariate analysis. However, the significance was marginal …’. The text should read ‘There was a trend towards worse outcomes in patients with a longer time between presentation and debridement (Table 1) on univariate analysis. However, the significance was marginal …’.

The authors apologize for these errors.


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