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. Author manuscript; available in PMC: 2013 Nov 14.
Published in final edited form as: Biochemistry. 2011 Nov 22;50(50):10.1021/bi200924t. doi: 10.1021/bi200924t

Figure 2. Determination of HS and LS by least squares fitting of 1 μM recombinant CYP3A4 heme absorbance spectra in the presence of 260 μM MDZ and 260 μM CBZ.

Figure 2

Absolute absorbance spectra of 1 μM CYP3A4 heme in the A) absence of ligands and in the presence of B) 260 μM MDZ, C) 260 μM CBZ and D) 260 μM MDZ and CBZ.