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. 1979 Mar;76(3):1435–1437. doi: 10.1073/pnas.76.3.1435

Influence of major histocompatibility haplotype on autoimmune disease varies in different inbred families of chickens.

L D Bacon, N R Rose
PMCID: PMC383266  PMID: 286327

Abstract

Three partially inbred substrains of Obese strain chickens were studied for the spontaneous development of autoimmune thyroiditis. The influence of the major histocompatibility complex (B haplotype) was marked in one, less marked but still significant in a second, and barely detectable and transient in a third substrain. These differences in the effect of B haplotype may be due to the overriding action of genes other than those within the B haplotype.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Albini B., Wick G. The influence of thymectomy on the development of erythrocyte-specific antinuclear factors in obese strain (OS) and normal white leghorn chickens. Immunology. 1973 Mar;24(3):545–549. [PMC free article] [PubMed] [Google Scholar]
  2. BRILES W. E., McGIBBON W. H., IRWIN M. R. On multiple alleles effecting cellular antigens in the chicken. Genetics. 1950 Nov;35(6):633–652. doi: 10.1093/genetics/35.6.633. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Bacon L. D., Kite J. H., Jr, Rose N. R. Immunogenetic detection of B locus genotypes in chickens with autoimmune thyroiditis. Transplantation. 1973 Dec;16(6):591–598. doi: 10.1097/00007890-197312000-00010. [DOI] [PubMed] [Google Scholar]
  4. Bacon L. D., Kite J. H., Jr, Rose N. R. Relation between the major histocompatibility (B) locus and autoimmune thyroiditis in obese chickens. Science. 1974 Oct 18;186(4160):274–275. doi: 10.1126/science.186.4160.274. [DOI] [PubMed] [Google Scholar]
  5. Benacerraf B., Kapp J. A., Debré P., Pierce C. W., de la Croix F. The stimulation of specific suppressor T cells in genetic non-responder mice by linear random copolymers of L-amino acids. Transplant Rev. 1975;26:21–38. doi: 10.1111/j.1600-065x.1975.tb00173.x. [DOI] [PubMed] [Google Scholar]
  6. Benacerraf B., McDevitt H. O. Histocompatibility-linked immune response genes. Science. 1972 Jan 21;175(4019):273–279. doi: 10.1126/science.175.4019.273. [DOI] [PubMed] [Google Scholar]
  7. Cole R. K. Hereditary hypothyroidism in the domestic fowl. Genetics. 1966 Jun;53(6):1021–1033. doi: 10.1093/genetics/53.6.1021. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Cole R. K., Kite J. H., Jr, Wick G., Witebsky E. Recent advances in avian endocrinology. 2. Inherited autoimmune thyroiditis in the fowl. Poult Sci. 1970 Jul;49(4):839–848. doi: 10.3382/ps.0490839. [DOI] [PubMed] [Google Scholar]
  9. Cole R. K., Kite J. H., Jr, Witebsky E. Hereditary autoimmune thyroiditis in the fowl. Science. 1968 Jun 21;160(3834):1357–1358. doi: 10.1126/science.160.3834.1357. [DOI] [PubMed] [Google Scholar]
  10. Günther E., Balcarová J., Hála K., Rüde E., Hraba T. Evidence for an association between immune responsiveness of chicken to (T, G)-A--L and the major histocompatibility system. Eur J Immunol. 1974 Aug;4(8):548–553. doi: 10.1002/eji.1830040806. [DOI] [PubMed] [Google Scholar]
  11. JAFFE W. P., McDERMID E. M. Blood groups and splenomegaly in chick embryos. Science. 1962 Sep 21;137(3534):984–984. doi: 10.1126/science.137.3534.984. [DOI] [PubMed] [Google Scholar]
  12. Jakobisiak M., Sundick R. S., Bacon L. D., Rose N. R. Abnormal response to minor histocompatibility antigens in Obese strain chickens. Proc Natl Acad Sci U S A. 1976 Aug;73(8):2877–2880. doi: 10.1073/pnas.73.8.2877. [DOI] [PMC free article] [PubMed] [Google Scholar]
  13. Jaroszewski J., Sundick R. S., Rose N. R. Effects of antiserum containing thyroglobulin antibody on the chicken thyroid gland. Clin Immunol Immunopathol. 1978 May;10(1):95–103. doi: 10.1016/0090-1229(78)90013-2. [DOI] [PubMed] [Google Scholar]
  14. Kite J. H., Jr, Wick G., Twarog B., Witebsky E. Spontaneous thyroiditis in an obese strain of chickens. II. Investigations on the development of the disease. J Immunol. 1969 Dec;103(6):1331–1341. [PubMed] [Google Scholar]
  15. Longenecker B. M., Pazderka F., Law G. R., Ruth R. F. Genetic control of graft-versus-host competence. Transplantation. 1972 Oct;14(4):424–431. doi: 10.1097/00007890-197210000-00003. [DOI] [PubMed] [Google Scholar]
  16. Luster M. I., Bacon L. D., Rose N. R., Leslie G. A. Immunogenetic and ontogenetic studies of chickens with selective IgA deficiency and autoimmune thyroiditis. Cell Immunol. 1977 Aug;32(2):417–423. doi: 10.1016/0008-8749(77)90217-9. [DOI] [PubMed] [Google Scholar]
  17. Rose N. R., Bacon L. D., Sundick R. S. Genetic determinants of thyroiditis in the OS chicken. Transplant Rev. 1976;31:264–285. doi: 10.1111/j.1600-065x.1976.tb01457.x. [DOI] [PubMed] [Google Scholar]
  18. SCHIERMAN L. W., NORDSKOG A. W. Relationship of blood type to histocompatibility in chickens. Science. 1961 Oct 6;134(3484):1008–1009. doi: 10.1126/science.134.3484.1008. [DOI] [PubMed] [Google Scholar]
  19. Tomazic V., Rose N. R., Shreffler D. C. Autoimmune murine thyroiditis. IV. Localization of genetic control of the immune response. J Immunol. 1974 Mar;112(3):965–969. [PubMed] [Google Scholar]
  20. Vladutiu A. O., Rose N. R. Autoimmune murine thyroiditis relation to histocompatibility (H-2) type. Science. 1971 Dec 10;174(4014):1137–1139. doi: 10.1126/science.174.4014.1137. [DOI] [PubMed] [Google Scholar]
  21. Welch P., Rose N. R., Kite J. H., Jr Neonatal thymectomy increases spontaneous autoimmune thyroiditis. J Immunol. 1973 Feb;110(2):575–577. [PubMed] [Google Scholar]
  22. Wernet P. Human Ia-type alloantigens: methods of detection, aspects of chemistry and biology, markers for disease states. Transplant Rev. 1976;30:271–298. doi: 10.1111/j.1600-065x.1976.tb00223.x. [DOI] [PubMed] [Google Scholar]
  23. Wick G., Kite J. H., Jr, Cole R. K., Witebsky E. Spontaneous thyroiditis in the obese strain of chickens. 3. The effect of bursectomy on the development of the disease. J Immunol. 1970 Jan;104(1):45–53. [PubMed] [Google Scholar]
  24. Wick G., Kite J. H., Jr, Witebsky E. Spontaneous thyroiditis in the obese strain of chickens. IV. The effect of thymectomy and thymo-bursectomy on the development of the disease. J Immunol. 1970 Jan;104(1):54–62. [PubMed] [Google Scholar]
  25. Witebsky E., Kite J. H., Jr, Wick G., Cole R. K. Spontaneous thyroiditis in the obese strain of chichens. I. Demonstration of circulating autoantibodies. J Immunol. 1969 Oct;103(4):708–715. [PubMed] [Google Scholar]

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