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. 1979 May;76(5):2222–2226. doi: 10.1073/pnas.76.5.2222

Cloning in Escherichia coli and physical structure of hepatitis B virion DNA.

P Charnay, C Pourcel, A Louise, A Fritsch, P Tiollais
PMCID: PMC383570  PMID: 377294

Abstract

A restriction map of hepatitis B virion DNA was established after cloning of the whole viral genome in Escherichia coli. By use of EcoRI, Xho I, Bgl II, Xba I, BamHI, HincII, and Hae III endonucleases, a total of 28 restriction sites were mapped. The single-stranded region was localized on the restriction map and 5' end of the short strand was mapped at a fixed position.

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Selected References

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