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. Author manuscript; available in PMC: 2013 Nov 21.
Published in final edited form as: Biochemistry. 2012 Jul 25;51(31):10.1021/bi300511w. doi: 10.1021/bi300511w

Table 4.

Kinetic Parameters of Bacterial IMPDH Proteins

B. anthracis Ca. jejuni Cl. perfringens V. cholerae
kcat (s−1) 1.4 ± 0.2 2.2 ± 0.3 0.6 ± 0.1 2.1 ± 0.2
Km(IMP) (μM) 18 ± 2 25 ±3 11 ± 2 80 ± 10
Km(NAD) (μM) 550 ± 50 220 ± 20 370 ± 4 1200 ± 200
Kii(NAD) (mM) 3.9 ± 0.5 20 ± 4 13 ± 2 naa
a

Not applicable.