Skip to main content
Proceedings of the National Academy of Sciences of the United States of America logoLink to Proceedings of the National Academy of Sciences of the United States of America
. 1979 Jun;76(6):2664–2668. doi: 10.1073/pnas.76.6.2664

Ion-channel component of cytochrome oxidase.

M Fry, D E Green
PMCID: PMC383668  PMID: 223154

Abstract

Cytochrome oxidase is resolvable into an electron transfer complex and an ion transfer complex. The ion transfer complex has been shown to have the capability for inducing nonspecific ion transport into liposomes. Subunit I of cytochrome oxidase has been identified as an ion-channel-forming protein.

Full text

PDF
2664

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Bangham A. D., Standish M. M., Weissmann G. The action of steroids and streptolysin S on the permeability of phospholipid structures to cations. J Mol Biol. 1965 Aug;13(1):253–259. doi: 10.1016/s0022-2836(65)80094-8. [DOI] [PubMed] [Google Scholar]
  2. Bittman R., Blau L. The phospholipid-cholesterol interaction. Kinetics of water permeability in liposomes. Biochemistry. 1972 Dec 5;11(25):4831–4839. doi: 10.1021/bi00775a029. [DOI] [PubMed] [Google Scholar]
  3. Downer N. W., Robinson N. C. Characterization of a seventh different subunit of beef heart cytochrome c oxidase. Similarities between the beef heart enzyme and that from other species. Biochemistry. 1976 Jun 29;15(13):2930–2936. doi: 10.1021/bi00658a036. [DOI] [PubMed] [Google Scholar]
  4. Eytan G. D., Broza R. Role of charge and fluidity in the incorporation of cytochrome oxidase into liposomes. J Biol Chem. 1978 May 10;253(9):3196–3202. [PubMed] [Google Scholar]
  5. Eytan G. D., Carroll R. C., Schatz G., Racker E. Arrangement of the subunits in solubilized and membrane-bound cytochrome c oxidase from bovine heart. J Biol Chem. 1975 Nov 25;250(22):8598–8603. [PubMed] [Google Scholar]
  6. Eytan G. D., Matheson M. J., Racker E. Incorporation of mitochondrial membrane proteins into liposomes containing acidic phospholipids. J Biol Chem. 1976 Nov 10;251(21):6831–6837. [PubMed] [Google Scholar]
  7. Eytan G. D., Schatz G. Cytochrome c oxidase from bakers' yeast. V. Arrangement of the subunits in the isolated and membrane-bound enzyme. J Biol Chem. 1975 Jan 25;250(2):767–774. [PubMed] [Google Scholar]
  8. Fry M., Green D. E. Resolution of complex III of the mitochondrial electron transfer chain into two component complexes. Proc Natl Acad Sci U S A. 1978 Nov;75(11):5377–5380. doi: 10.1073/pnas.75.11.5377. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. Fry M., Vande Zande H., Green D. E. Resolution of cytochrome oxidase into two component complexes. Proc Natl Acad Sci U S A. 1978 Dec;75(12):5908–5911. doi: 10.1073/pnas.75.12.5908. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Green D. E., Blondin G. A. Molecular mechanism of mitochondrial energy coupling. Bioscience. 1978 Jan;28(1):18–24. [PubMed] [Google Scholar]
  11. Green D. E., Reible S. Paired moving charges in mitochondrial energy coupling. Proc Natl Acad Sci U S A. 1974 Dec;71(12):4850–4854. doi: 10.1073/pnas.71.12.4850. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. Harmon H. J., Hall J. D., Crane F. L. Structure of mitochondrial cristae membranes. Biochim Biophys Acta. 1974 Sep 16;344(2):119–155. doi: 10.1016/0304-4157(74)90002-1. [DOI] [PubMed] [Google Scholar]
  13. Hinkle P. C., Kim J. J., Racker E. Ion transport and respiratory control in vesicles formed from cytochrome oxidase and phospholipids. J Biol Chem. 1972 Feb 25;247(4):1338–1339. [PubMed] [Google Scholar]
  14. Huang C. Studies on phosphatidylcholine vesicles. Formation and physical characteristics. Biochemistry. 1969 Jan;8(1):344–352. doi: 10.1021/bi00829a048. [DOI] [PubMed] [Google Scholar]
  15. Hunter D. R., Capaldi R. A. Respiratory control in cytochrome oxidase. Biochem Biophys Res Commun. 1974 Feb 4;56(3):623–628. doi: 10.1016/0006-291x(74)90650-0. [DOI] [PubMed] [Google Scholar]
  16. Jain M. K., Touissaint D. G., Cordes E. H. Kinetics of water penetration into unsonicated liposomes. Effects of n-alkanols and cholesterol. J Membr Biol. 1973 Dec 6;14(1):1–16. doi: 10.1007/BF01868065. [DOI] [PubMed] [Google Scholar]
  17. Kagawa Y., Johnson L. W., Racker E. Activation of phosphorylating vesicles by net transfer of phosphatidyl choline by phospholipid transfer protein. Biochem Biophys Res Commun. 1973 Jan 23;50(2):245–251. doi: 10.1016/0006-291x(73)90832-2. [DOI] [PubMed] [Google Scholar]
  18. Kagawa Y. Reconstitution of the energy transformer, gate and channel subunit reassembly, crystalline ATPase and ATP synthesis. Biochim Biophys Acta. 1978 Sep 21;505(1):45–93. doi: 10.1016/0304-4173(78)90008-3. [DOI] [PubMed] [Google Scholar]
  19. Kessler R. J., Blondin G. A., Vande Zander H., Haworth R. A., Green D. E. Coupling in cytochrome c oxidase. Proc Natl Acad Sci U S A. 1977 Sep;74(9):3662–3666. doi: 10.1073/pnas.74.9.3662. [DOI] [PMC free article] [PubMed] [Google Scholar]
  20. Mason T. L., Schatz G. Cytochrome c oxidase from bakers' yeast. II. Site of translation of the protein components. J Biol Chem. 1973 Feb 25;248(4):1355–1360. [PubMed] [Google Scholar]
  21. Phan S. H., Mahler H. R. Studies on cytochrome oxidase. Preliminary characterization of an enzyme containing only four subunits. J Biol Chem. 1976 Jan 25;251(2):270–276. [PubMed] [Google Scholar]
  22. Poyton R. O., Schatz G. Cytochrome c oxidase from bakers' yeast. III. Physical characterization of isolated subunits and chemical evidence for two different classes of polypeptides. J Biol Chem. 1975 Jan 25;250(2):752–761. [PubMed] [Google Scholar]
  23. Swank R. T., Munkres K. D. Molecular weight analysis of oligopeptides by electrophoresis in polyacrylamide gel with sodium dodecyl sulfate. Anal Biochem. 1971 Feb;39(2):462–477. doi: 10.1016/0003-2697(71)90436-2. [DOI] [PubMed] [Google Scholar]
  24. Tzagoloff A., Meagher P. Assesmbly of the mitochondrial membrane system. VI. Mitochondrial synthesis of subunit proteins of the rutamycin-sensitive adenosine triphosphatase. J Biol Chem. 1972 Jan 25;247(2):594–603. [PubMed] [Google Scholar]
  25. Urry D. W., Long M. M., Jacobs M., Harris R. D. Conformation and molecular mechanisms of carriers and channels. Ann N Y Acad Sci. 1975 Dec 30;264:203–220. doi: 10.1111/j.1749-6632.1975.tb31484.x. [DOI] [PubMed] [Google Scholar]
  26. Yu C., Yu L. Identification of subunits of bovine heart cytochrome oxidase. Biochim Biophys Acta. 1977 Dec 20;495(2):248–259. doi: 10.1016/0005-2795(77)90381-6. [DOI] [PubMed] [Google Scholar]
  27. de Gier J., Mandersloot J. G., van Deenen L. L. Lipid composition and permeability of liposomes. Biochim Biophys Acta. 1968 Jun 11;150(4):666–675. doi: 10.1016/0005-2736(68)90056-4. [DOI] [PubMed] [Google Scholar]

Articles from Proceedings of the National Academy of Sciences of the United States of America are provided here courtesy of National Academy of Sciences

RESOURCES