Table 3.

Immune markers in the CSF and plasma of HIV-infected humans on ART with long term viral suppression.

Immune markers	HIV negative	HIV positive Visit A	HIV positive Visit B	*P value (HIV negative versus Visit A)	#P value (Visit A versus B)
Plasma sCD163 ng/ml	871.3 ± 55.6	1343.0 ± 161.4	1122.9 ± 123.7	0.01	0.01
Plasma sCD14 ng/ml	1353 ± 251.6	1983.5 ± 251.6	2070.7 ± 248.3	0.03	NS
CSF MCP-1 ng/ml	467.7 ± 25.5	548.7 ± 52.3	500.0 ± 27.0	NS	NS
CSF Neopterin nmol/l	17.5 ± 3.8	181.8 ± 15.7	123.2 ± 17.8	<0.0001	0.05
CSF sCD163 ng/ml	71.1 ± 9.0	65.2 ± 7.7	73.6 ± 10.5	NS	NS
CSF sCD14 ng/ml	132.4 ± 12.4	105.5 ± 10.5	110.0 ± 7.6	NS	NS

Mean ± SEM of immune markers measured in HIV-negative individuals and HIV-positive individuals at visit A and B.

^*Student t-tests were performed between HIV-negative and HIV-positive patients at visit A.

^#Paired t-tests were performed between visits A and B to determine if there was statistical significance between the groups. NS, not significant, P value more than 0.05.