Figure 5.

Asymptotic growth of the search space as a function of protein length N (on a log–linear plot). The search spaces grow exponentially with N, for all choices of L, M, and F. The rate of growth increases with increases in fragment library size F and fragment length L (a and b), but decreases for larger move sizes M (c). If M and L are varied together, the trends observed for L and M cancel out and we observe an identical rate of growth (with different offsets) for all choices of L = M (d). [Color figure can be viewed in the online issue, which is available at wileyonlinelibrary.com.]